PANCREATICODUODENECTOMY: RETROSPECTIVE STUDY OF A SINGLE CENTER EXPERIENCE

Abstract

Background: Whipple surgery (pancreaticoduodenectomy) is a complex surgery with high postoperative complication rate. We aimed to demonstrate the outcomes and rates of complications from patients who had undergone PD in our hospital. Materials and methods: Medical records of 22 patients, who underwent pancreaticoduodenectomy surgery between November 2018 and December 2022 at Department of Abdominal Surgery, City General Hospital 8th September in Skopje, North Macedonia, were examined retrospectively. Age, sex, localization of the lesion and pathohistological properties and postoperative morbidity and mortality were studied. Results: A total of 22 patients (12 male, 10 female) with a mean age of 63,9 years who underwent pancreaticoduodenectomy were included in the study. Ten patients (45,45%) had pancreatic head malignancies, 7 patients (31,81%) had ampullarry malignancies, 1 patient (4,54%) had duodenal and also 1 patient (4,54%) had common bile duct malignancies. Two of our cases (9,08%) underwent surgery for gastric antrum carcinoma and one patient (4,54%) for colon carcinoma. The most frequently encountered complications were pancreatic fistula (18,16%), biliary leakage (13,64%) and pulmonary complications (13,64%). Surgery related mortality rate was 9,09% (2 cases). Conclusion: We represent outcomes of our surgical team compared to the published data of some other centers. Prospective randomized studies are needed to adequately assess postoperative complications. To improve the postoperative outcome, appropriate monitoring, multidisciplinary approach and further improving of surgical techniques are needed.