Lymphoid Interstitial Pneumonia

Abstract

This study explores the distinctive imaging features of Lymphoid Interstitial Pneumonia (LIP) through a comprehensive HRCT analysis. Highlighting the role of HRCT in diagnosis, the report emphasizes key patterns crucial for recognizing and intervening in LIP cases. In a 47-year-old male with non-specific respiratory symptoms, inconclusive clinical and laboratory data prompted HRCT, revealing diffuse mid to lower lobe-predominant changes. Noteworthy findings included bronchovascular bundle thickening, interstitial thickening along lymph channels, variablesized pulmonary nodules, ground-glass changes, and scattered thin-walled cysts adjacent to vessels, leading to a precise LIP diagnosis. HRCT showcased characteristic LIP features—diffuse mid to lower lobepredominant changes, bronchovascular bundle thickening, interstitial thickening along lymph channels, variable-sized pulmonary nodules, ground-glass changes, and distinctive thin-walled cysts near vessels. Mediastinal lymphadenopathy further validated the specificity of LIP findings. The study discusses the distinctive nature of LIP's imaging findings, particularly scattered thin-walled cysts and mediastinal lymphadenopathy, setting it apart from other lung pathologies. Radiologic-pathologic correlation aids in understanding LIP's complex features. This case underscores the crucial role of HRCT in diagnosing LIP accurately and differentiating it from other interstitial lung diseases. A nuanced understanding of HRCT findings serves as a cornerstone in navigating the complexities of LIP, guiding clinicians toward optimal patient management. Keywords: lymphoid interstitial pneumonia (LIP), high resolution CT (HRCT), thin-walled cysts, ground glass changes.