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Title: | Effect of oral calcium carbonate on aortic calcification in apolipoprotein E-deficient (apoE-/-) mice with chronic renal failure | Authors: | Phan, Olivier Ivanovski, Ognen Nikolov, Igor G Joki, Nobuhiko Maizel, Julien Louvet, Loïc Chasseraud, Maud Nguyen-Khoa, Thao Lacour, Bernard Drüeke, Tilman B Massy, Ziad A |
Issue Date: | Jan-2008 | Publisher: | Oxford University Press (OUP) | Journal: | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | Abstract: | In chronic kidney disease (CKD) patients, the intake of calcium-based phosphate binders is associated with a marked progression of coronary artery and aortic calcification, in contrast to patients receiving calcium-free phosphate binders. The aim of this study was to reexamine the role of calcium carbonate in vascular calcification and to analyse its effect on aortic calcification-related gene expression in chronic renal failure (CRF). | URI: | http://hdl.handle.net/20.500.12188/9602 | ISSN: | 0931-0509 | DOI: | 10.1093/ndt/gfm699 |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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