Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/11750
Title: | Widespread frontal lobe cortical dysplasia or partial hemimegalencephaly: a continuum of the spectrum | Authors: | Emilija Cvetkovska Kuzmanovski Igor Boskovski Bojan Babunovska Marija Kiteva Trencevska, Gordana |
Keywords: | cortical dysplasia epilepsy frontal lobe partial hemimegalencephaly |
Issue Date: | Oct-2019 | Publisher: | Wiley Online Library | Journal: | Epileptic Disorders | Abstract: | Focal cortical dysplasia (FCD) type II and hemimegalencephaly (HME) are currently considered as a continuum of pathology, the most important distinction being the extent or the size/volume of the lesion. While partial HME involving the posterior cortex has been well described, we present an unusual case with a dysplastic lesion of the whole frontal lobe. A 17-year-old boy had focal seizures from the age of nine years. Apart from diminished right-hand dexterity, his neurological and cognitive status were unremarkable. The course of his epilepsy exhibited a relapsing-remitting pattern, with prolonged periods of remission. Imaging showed dysplastic left frontal lobe (including paracentral lobule) thickened cortex with an abnormal gyration pattern resembling polymicrogyria, as well as dystrophic calcifications and hypodensity scattered throughout the white matter. This patient represents an intermediate case within the FCD type II/HME spectrum. Localization of the lesion in the frontal lobe as well as clinical characteristics (childhood onset, relapsing-remitting epilepsy, without hemiparesis and overt cognitive impairment) are more consistent with FCD type II, while a range of MRI features is shared between HME and FCD type II. | URI: | http://hdl.handle.net/20.500.12188/11750 | DOI: | 10.1684/epd.2019.1101 |
Appears in Collections: | Faculty of Medicine: Journal Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
epd-315407-43812-widespread_frontal_lobe_cortical_dysplasia_or_partial_hemimegalencephaly_a_continuum_of_the_spectrum-gkitevatrencevska-u.pdf | 1.43 MB | Adobe PDF | View/Open |
Page view(s)
88
checked on Jul 24, 2024
Download(s)
25
checked on Jul 24, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.